Skype is an essential tool for a digital nomad. In some versions of gnu/Linux, you'll notice considerable audio quality issues and disturbance (white noise) in Skype. Had to resort to using Skype on Android until I found this solution on Skype community forum.
Run this command in the terminal to start Skype. You'll notice significant improvement in the audio quality.
$ PULSE_LATENCY_MSEC=30 skype